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pentobarbital will lessen the extent or result of sulfamethoxazole by impacting hepatic enzyme CYP2C9/ten metabolism. slight/importance Unknown.
pentobarbital will lessen the level or outcome of nicardipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use warning/keep an eye on.
far too rapid administration may well result in respiratory despair, laryngospasm, apnea, or vasodilation with tumble in hypertension
pentobarbital will decrease the extent or influence of cevimeline by impacting hepatic/intestinal enzyme CYP3A4 website metabolism. Minor/Significance mysterious.
pentobarbital will decrease the level or result of roflumilast by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration not suggested; solid cytochrome P450 enzyme inducers lessen systemic exposure to roflumilast and should reduce the therapeutic performance
Avoid; coadministration with CYP3A inducers may perhaps result in reduced plasma concentrations of elvitegravir and/or possibly a concomitantly administered protease inhibitor and produce lack of therapeutic outcome also to attainable resistance
pentobarbital will reduce the level or result of tramadol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use warning/keep an eye on. diminished AUC of tramadol along with the Lively metabolite (O-desmethyltramadol) when coadministered with solid CYP3A4 and CYP2B6 inducers
pentobarbital will reduce the extent or influence of mavacamten by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will minimize the level or result of guanfacine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/keep track of carefully. powerful or moderate CYP3A4 inducers appreciably decrease guanfacine plasma concentrations and elimination half-lifetime.
pentobarbital will decrease the level or result of flurbiprofen by affecting hepatic enzyme CYP2C9/10 metabolism. insignificant/Significance unidentified.
pentobarbital will minimize the level or effect of bosentan by affecting hepatic enzyme CYP2C9/ten metabolism. small/importance not known.
pentobarbital will minimize the level or impact of linagliptin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Use of other treatments is strongly advisable when linagliptin would be to be administered with a CYP3A4 inducer
pentobarbital will decrease the level or outcome of tadalafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/keep track of. steer clear of blend in pulmonary HTN clients. For clients with ED, observe response to tadalafil meticulously due to likely for reduced performance.
pentobarbital will lessen the level or outcome of fedratinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Effect of coadministering a strong CYP3A4 inducer with fedratinib hasn't been studied.